ISSN: 2155-6148
+44 1223 790975
Adel Ragheb
Egypt
Research Article
Recombinant Activated Factor VII (rFVIIa) Treatment of Refractory Bleeding in Cardiac Surgical Patients
Author(s): Rabie Soliman, Makhlouf Belghith, Hassan Yousef, Faisal Alghadam and Adel RaghebRabie Soliman, Makhlouf Belghith, Hassan Yousef, Faisal Alghadam and Adel Ragheb
Objective: Our aim to evaluate the efficacy and safety of rFVIIa in cardiac surgical patients with refractory bleeding. Design: The study was a retrospective study. Setting: Prince Sultan cardiac center, Saudia Arabia. Participants: Data were collected in patients who had undergone cardiac surgery and complicated by refractory bleeding. The study included 35 patients adults and 8 children. Interventions: rFVIIa administration. Measurements and main results: The rFVIIa effect was assessed by the decrease in the chest blood loss (The amount of bleeding was < 3ml/kg/hr without accumulation of blood inside the chest) and number of blood products (Packed red blood cells, platelets, fresh frozen plasma, and cryoprecipitate) given before and after rFVIIa administration was recorded. The dose of rFVIIa was 93.72 ± 17.39 μg/kg. All patients received single dose of rFVIIa, but nine.. View More»
DOI:
10.4172/2155-6148.1000200