Reproductive System & Sexual Disorders: Current Research
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Akinrinade ID

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• Review Article
  Histological Integrity of the Testis of Adult Wistar Rats (Rattus novergicus) Treated with Garcinia kola
  Author(s): Dare BJ, Chukwu RO, Oyewopo AO, Makanjuola VO, Olayinka PO, Akinrinade ID, Olaniyan TO, Omotoso OD, Shafe MO, Ogundele OM, Beremako OO and Adeh MN Dare BJ, Chukwu RO, Oyewopo AO, Makanjuola VO, Olayinka PO, Akinrinade ID, Olaniyan TO, Omotoso OD, Shafe MO, Ogundele OM, Beremako OO and Adeh MN
  
  Garcinia kola has been confirmed for spermatogenic and tissue enhancing effect of testis in male wistar rats. This study was carried out to investigate the histological effect of ethanolic extract of Garcinia kola on Lead II oxide induced testicular damage. Thirty five (35) adult male wistar rats were randomly selected into seven (7) groups n=5. Group A received 0.5 ml saline solution, Group B received 100 mg/kg of Garcinia kola extract only, Group C received 5 mg/kg of Lead II oxide only, Group D1 received 100 mg/kg of Garcinia kola extract and 5 mg/kg of Lead II oxide, Group D2 received 200 mg/kg of Garcinia kola extract and 5 mg/kg of Lead II oxide, Group E received 500 mg/kg of vitamin E only and Group F received 500 mg/kg of vitamin E and 5 mg/kg Lead II oxide. Administration was done orogastrically daily for 2 weeks, animals were sacrificed 24 h.. View More»
  DOI: 10.4172/2161-038X.1000113

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