Chemotherapy: Open Access
Open Access

Akira Tadokoro

Publications

• Case Report
  Delayed onset, Long-term Efficacy of S-1 Monotherapy for an Elderly Patient with Squamous Cell Lung Cancer
  Author(s): Nobuhiro Kanaji, Nobuki Nanki, Akira Tadokoro and Shuji Bandoh Nobuhiro Kanaji, Nobuki Nanki, Akira Tadokoro and Shuji Bandoh
  
  The efficacy of S-1 monotherapy as a 2nd-line regimen for elderly patients with non-small cell lung cancer (NSCLC) has not been reported, nor has delayed onset regression after temporary progression of tumor during an identified therapeutic regimen. Here we report a 78-year-old man was diagnosed with T3N3M1b (BRA), stage IV squamous cell lung cancer. His primary lesion progressed after whole brain irradiation and 4 cycles of 1st-line chemotherapy with docetaxel. S-1 monotherapy was prescribed as the 2nd-line treatment. Each cycle of chemotherapy comprised 14 days of S-1 (40 mg, twice daily) followed by 14 drug-free days. After 6 months of S-1 monotherapy, primary and metastatic lesions had started regressing significantly. He continued S-1 monotherapy for 19 months (20 cycles) with a comfortable daily life until reaching progressive disease. S-1 monotherapy as a 2nd-line could be a th.. View More»
  DOI: 10.4172/2167-7700.1000139

  Abstract PDF

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