Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Alberto Cornejo
Faculty of Medicine, School of Medical Technology, Andrés Bello University,
Sazié 2315, First Floor, Santiago 8370092
Chile
Commentary
Secondary Metabolites of Lichens as Both Anti-aggregative and Antioxidant Agents in Tauopathies
Author(s): Alberto Cornejo and Carlos Areche
Alberto Cornejo and Carlos Areche
This commentary described our findings of parietin, an anthraquinone, isolated from Ramalina terebrata as inhibitor of tau protein. Moreover, we considered important to link tauopathies with reactive oxygen species since oligomers and fibril-forming elements are responsible for activating reactive oxygen species, which cause inflammatory response and neurodegeneration. Together, we considered important to find naturally occurring compounds that might be able to stop aggregation and reduces ROS cells damage.
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DOI:
10.4172/2155-9899.1000496