Rheumatology: Current Research
Open Access

Alexandria Voigt

Publications

• Review Article
  Beyond the Glands: An in-Depth Perspective of Neurological Manifestations in Sjögren’s Syndrome
  Author(s): Alexandria Voigt, Sukesh Sukumaran and Cuong Q NguyenAlexandria Voigt, Sukesh Sukumaran and Cuong Q Nguyen
  
  Primary Sjögren’s Syndrome (pSjS) is an autoimmune disease characterized by sicca (xerophthalmia or xerostomia) symptoms, anti-SS-A (Ro) or anti-SS-B (La) autoantibodies, and lymphocytic infiltrates in the exocrine glands. Disease incidence is estimated to be 0.1-3% of the general population with 0.4-3.1 million individuals in the US with women being nine times more likely to be afflicted with SjS than men. The frequency continues to rise accompanied with the multi-factorial etiology making it a challenging disease to manage and treat. Treatment of this disease remains problematic due to the lack of therapeutic treatments relying on replacement therapies such as artificial saliva and eye lubricants or immunosuppressive agents. To further complicate the management of the disease, there are number of multi-systemic manifestations specifically peripheral neuropathy associated .. View More»
  DOI: 10.4172/2161-1149.S4-010

  Abstract PDF

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