Rheumatology: Current Research
Open Access

Ali Sahin

Publications

• Research Article
  The Effect of Oxidative Stress on Pulmonary Involvement in Patients with Systemic Sclerosis
  Author(s): Sukran Erten, Tahsin Murat Turgay, Erdinc Devrim, Serdal Kenan Kose, Berrin Imge Erguder, Ilker Durak, Orhan Kucuksahin, Ali Sahin, Alexis K OKOH and Emre Kulahcioglu Sukran Erten, Tahsin Murat Turgay, Erdinc Devrim, Serdal Kenan Kose, Berrin Imge Erguder, Ilker Durak, Orhan Kucuksahin, Ali Sahin, Alexis K OKOH and Emre Kulahcioglu
  
  Introduction: The aim of this study was to evaluate the relationship between oxidative stress and pulmonary involvement and its severity in patients with systemic sclerosis (SSc). Materials and Methods: 34 patients (30 female, 4 male) and 27 healthy volunteers (21 female, 6 male) were included into the study. All patients fullfilled the American College of Rheumatology criteria for the diagnosis of SSc. Oxidant-antioxidant enzymes malondialdehyde (MDA), Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-PX), xanthine oxidase (XO), and adenosine deaminase (ADA) enzyme activities were measured by spectrophotometric methods. Results: Plasma ADA levels was significantly higher in patients than the control group. On contrary, XO levels of erythroctes were lower. Of 34 patients, 11 had no p.. View More»
  DOI: 10.4172/2161-1149.1000171

  Abstract PDF

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