Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

Amal Kamal Helmy

Publications
  • Research Article
    Evaluation of the Diagnostic Performance of Soluble Human Leukocyte Antigen- G versus α-Fetoprotein for Hepatitis C Virus-Induced Hepatocellular Carcinoma
    Author(s): Amel Mahmoud Kamal Eldin, Manal Mohamed Saber, Aliaa Higazi, Amal Kamal Helmy, Hala Ibrahem Mohamed and Asmaa Ahmed Aly Amel Mahmoud Kamal Eldin, Manal Mohamed Saber, Aliaa Higazi, Amal Kamal Helmy, Hala Ibrahem Mohamed and Asmaa Ahmed Aly

    Background: Hepatocellular carcinoma (HCC) is the leading cause of death in HCV-related liver diseases and the third most common cause of cancer-related mortality worldwide. A reliable serum marker for early diagnosis of HCC is currently lacking. Objectives: The aim of this study was to identify the serum levels of soluble Human leukocyte antigen-G (sHLAG) in HCC and liver cirrhosis (LC) patients. As well, we aimed to estimate the diagnostic performance of sHLA-G for HCC by comparing its levels with the levels of Alpha fetoprotein (AFP). Subjects and methods: The study included 100 subjects divided into: 25 apparently healthy volunteers who served as healthy control subjects (group I), and 50 patients with untreated HCC on top of liver cirrhosis (group II) in addition to 25 cirrhotic patients (group III). HCC group was d.. View More»
    DOI: 10.4172/2155-9899.1000433

    Abstract PDF

Relevant Topics

Top