Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Amandeep Singh
Shri Guru Ram Rai Institute of Medical and Health Sciences,
Patel Nagar, Dehradun, Uttarakhand– 248001
India
Research Article
To Compare the Safety, Efficacy and Quality of Life in Patients with Allergic Rhinitis Treated with Levocetirizine and Desloratadine
Author(s): Divya Chawla, Amandeep Singh, Manish Gupta, Prithpal S Matreja and P M L KhannaDivya Chawla, Amandeep Singh, Manish Gupta, Prithpal S Matreja and P M L Khanna
Background: Allergic Rhinitis (AR) is a very common disease that affects almost 10-30% of the world’s population. Second-generation H1 antihistaminics are the preferred drugs for treatment of patients with AR. Levocetirizine and desloratadine are commonly prescribed newer non-sedating second-generation antihistaminics. Various studies show no difference in efficacy and quality of life (QOL) between the two drugs desloratadine and levocetirizine and that the drugs are quiet safe; however, some studies show negative impact on patients’ QOL with these drugs. Studies comparing the two drugs were insufficient in India; hence, this study was designed to evaluate and compare the efficacy, safety and QOL of patients with AR, following treatment with levocetirizine or desloratadine, in the Indian scenario.Methods: This 2-month randomized, pro.. View More»
DOI:
10.4172/2155-9899.1000216