Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

+44 1223 790975

Ameera Kamal Khalil

Ameera Kamal Khalil
College of Dentistry,
Erbil, Iraqi Kurdistan
Iraq

Publications
  • Research Article
    Effect of Chamomile Extract on the Tongue of Chemotherapy Treated Albino Rats (Histopathological and Immunohistochemical Study)
    Author(s): Ali Sultan Al-Refai, Othman A. Omar and Ameera Kamal KhalilAli Sultan Al-Refai, Othman A. Omar and Ameera Kamal Khalil

    Background and objectives: 5-Fluorouracil (5-FU) is a commonly used drug for the treatment of malignant cancers. The control of oral mucositis result from 5-FU use is becoming increasingly more important, and effective intervention is considered a high priority in cancer patient care. The aim of this study was to investigate the effect of chamomile extract on the pathogenesis of 5-FU induced tongue mucositis in Albino rat.Materials and methods: In current study forty female Albino rats, weighing 220-280 g were used. For the induction of mucositis, 60 mg/kg of 5-FU was administered intraperitoneally to each animal in the study group on day 0, and 40 mg/kg was administered on day 2. The control animals were intraperitoneally injected by normal saline in the same manner and dose like 5-FU on day 0 and 2. Then the rats in each group were randomly di.. View More»
    DOI: 10.4172/2155-9899.1000251

    Abstract PDF

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