Journal of Clinical Chemistry and Laboratory Medicine
Open Access
ISSN: 2736-6588
ISSN: 2736-6588
Amir Hassan Matini
West Indies
Research Article
Relationship between Serum Leptin and Adiponectin Levels with Severity of Psoriasis
Author(s): Rezvan Talaei, Batool Zamani, Amir Hassan Matini, Seyyed Alireza Morawegi, Rabi Mazloomi, Zaynab Aalipour and Hamidreza Masror
Rezvan Talaei, Batool Zamani, Amir Hassan Matini, Seyyed Alireza Morawegi, Rabi Mazloomi, Zaynab Aalipour and Hamidreza Masror
Introduction: Psoriasis is a common, chronic, inflammatory and proliferative disease of the skin that is associated with obesity, cardiovascular disease, diabetes and metabolic syndrome. Adiponectin and leptin bioactive substances are secreted from adipose tissue and contribute to the pathogenesis of inflammatory and autoimmune diseases such as psoriasis. The aim of this study was to determine the relationship between serum leptin and adiponectin levels with the severity of psoriasis.
Materials and methods: This cross-sectional study was performed on 110 patients with psoriasis. After the registration of the demographic characteristics of the patients, the severity of psoriasis was measured by PASI index and then the serum leptin and adiponectin levels were measured. Data were entered to SPSS software and analyzed by Chi-square, Fisher's ex.. View More»