Clinical & Experimental Cardiology
Open Access

Anderson T

Publications

• Research Article
  Magnetic Resonance Elastography through Atherosclerosis: A Feasibility Study
  Author(s): Thomas-Seale LEJ*, Kennedy P, Hollis L, Hammer S, Anderson T, Mirsadraee S, Klatt D, Sack I, Pankaj P, Roberts N and Hoskins PRThomas-Seale LEJ*, Kennedy P, Hollis L, Hammer S, Anderson T, Mirsadraee S, Klatt D, Sack I, Pankaj P, Roberts N and Hoskins PR
  
  It is widely acknowledged that assessing the rupture risk of atherosclerotic plaques, via lumen reduction, is an imperfect criterion and that other properties such as those related to biomechanics may be more relevant. This study investigated the hypothesis that magnetic resonance elastography (MRE) can be used to image the elasticity of atherosclerotic plaques with the aim to give a better indication of rupture risk. Atherosclerotic plaques were imaged through a small feasibility data set including stenosed arterial phantoms, healthy volunteers and peripheral artery disease (PAD) patients. Comparison of the healthy volunteer and PAD patient wave displacement images showed differences in noise levels, wave amplitudes and wave propagation through the lumen. However, the change in shear moduli through healthy and diseased areas of the phantoms and in vivo subjects could.. View More»
  DOI: 10.4172/2155-9880.1000481

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