Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Andi Husni Tanra
Uganda
Research Article
The Antinociceptive Effects of Pregabalin on Post-Operative Hysterectomy Patient
Author(s): Leonardo Alfonsius Paulus Lalenoh, Hermanus Jacobus Lalenoh, Andi Husni Tanra and Irawan YusufLeonardo Alfonsius Paulus Lalenoh, Hermanus Jacobus Lalenoh, Andi Husni Tanra and Irawan Yusuf
Postoperative pain experienced by patients who completed surgery should receive serious attention, because of effective postoperative pain management will reduce morbidity and mortality, accelerate the mobilization and reducing hospitalization time of patients. These studies aim to determine the effect of pregabalin on antinociception and substan-glutamate levels in the blood of patients with postoperative P hysterectomy. This research is an experimental study, namely the Controlled Trial Randomized clinical trials in which patients were randomly divided into two groups by the number of patients who be included 52 people (aged 20-50 years) who underwent hysterectomy surgery. They were divided into group I (n=26) orally administered pregabalin 3 mg/kg body weight and group II (n=26) placebo given orally, 1 hour before surgery. All patients are given general anesthesia that premedicatio.. View More»
DOI:
10.4172/2155-6148.1000466