Clinical & Experimental Cardiology
Open Access

Andrea Piccioni

Publications

• Case Report
  A Case of Symptomatic Hypertrophic Cardiomyopathy with Severe Dynamic Gradient
  Author(s): Andrea Piccioni*, Marinella Mazzone, Fabrizio Lupparelli, Claudia Mandolini, Giulia Ciocci, Manfredi de Marle Giusti, Cacciotti Luca, Gerardo Ansalone and Cinzia Sighieri Andrea Piccioni*, Marinella Mazzone, Fabrizio Lupparelli, Claudia Mandolini, Giulia Ciocci, Manfredi de Marle Giusti, Cacciotti Luca, Gerardo Ansalone and Cinzia Sighieri
  
  Hypertrophic cardiomyopathy is a disease of the myocardium characterized by the thickening of the heart walls. It is a genetic disorder transmitted by first-degree relatives, caused by mutations in genes that code for sarcomere protein. A 77-year-old woman presented to the emergency department and complained of continuous vertigos and presyncope with subsequent fall to the floor with a concussive traumatic brain injury. The ECG observed signs of left ventricular hypertrophy. Blood exams highlighted a slight increase of troponin T (25 ng/L). The ultrosonography instead demonstrated a pronounced left ventricular hypertrophy with a 240 mmHg dynamic gradient, a moderate mitral regurgitation secondary to SAM. Lastly, ECG Holter excluded significant arrhythmias (1 couple of ventricular contractions). In the ward, the echocardiographic pattern was repeated and confirmed the clinica.. View More»
  DOI: 10.4172/2155-9880.1000506

  Abstract PDF

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