Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Angela Herro
Tanzania
Research Article
Incidence of Corneal Melt in Clinical Practice: Our Experience vs. A Meta-Analysis of the Literature
Author(s): Michael Singer, Mario Del Cid, Jennifer Luth, Salman S Porbandarwalla, Angela Herro, Joe Pollard and Paul WoodsMichael Singer, Mario Del Cid, Jennifer Luth, Salman S Porbandarwalla, Angela Herro, Joe Pollard and Paul Woods
Purpose: To evaluate the long-term safety of NSAID drops and incidence of corneal melt including contributing factors when bromfenac, ketorolac, or nepafenac are used long-term at a dosing frequency (up to four-times daily) in patients with macular edema secondary to macular cysts, full thickness macular holes, ERM, or cystoid macular edema. A comparison of our practices safety data was compared to historically reported data to try to identify incidence rates of corneal melt as well as to identify risk factors to help predict patients at-risk.Methods: IRB Approved retrospective review of 501 patient records, divided evenly between bromfenac, ketorolac, and nepafenac (n=167 each). Patients were on the NSAID for at least 3 months and not greater than 120 months (10 years). Data collected included the NSAID prescribed, time on the NSAID (in months).. View More»
DOI:
10.4172/2155-9570.S1-003