Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

Anitadevi Krishnan

Publications
  • Review Article
    Two Dimensional Gel Electrophoresis: An Overview of Proteomic Technique in Cancer Research
    Author(s): Saeid R Doustjalali, Munira Bhuiyan, Karim Al-Jashamy, Nyan Htain Linn, Samiah Yasmin Abdul Kadir, Vinothini Appalanaidu, Hafiza Arzuman, Anitadevi Krishnan, Wai Ma Lin, Alireza Saraji, Kaliappan Gopal, Esaki Muthu Shankar, Shahhosseini Fatemeh and Negar S Sabet Saeid R Doustjalali, Munira Bhuiyan, Karim Al-Jashamy, Nyan Htain Linn, Samiah Yasmin Abdul Kadir, Vinothini Appalanaidu, Hafiza Arzuman, Anitadevi Krishnan, Wai Ma Lin, Alireza Saraji, Kaliappan Gopal, Esaki Muthu Shankar, Shahhosseini Fatemeh and Negar S Sabet

    Proteomics can widely be used as one of the tool for protein level analysis which has largely become a necessity because the study of genes by genomics might not be adequately predict the structural dynamics of proteins. There is, however, a strong and synergistic relationship between proteomics and genomics as the two disciplines investigate the molecular organization of the cell at the complementary levels and increase the effectiveness of each other. In proteomics, the most promising technique with sufficient resolving power is two-dimensional gel electrophoresis (2DE) that provides a unique platform for the simultaneous separation of proteins in a complex mixture. However, the performance of optimization techniques in proteomics research using 2DE has its own limitations. In order to overcome these limitations, herein we have aime.. View More»
    DOI: 10.4172/jpb.1000305

    Abstract PDF

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