Journal of Cell Science & Therapy
Open Access

Antoine de Morrée

Publications

• Editorial
  Unifying Disease Mechanisms; Looking at Similarities and Differences
  Author(s): Antoine de MorréeAntoine de Morrée
  
  In the past century the medical sciences have made great strides in diagnostics by using a reductionist approach. Complex disease phenotypes have been meticulously dissected molecularly often resulting in clear genetic definitions. However, the development of therapies is lagging behind our ability to screen and diagnose these diseases in the lab. One reason for the lag in therapy development may be that our enhanced diagnostic capacity has led to the definition of many orphan diseases; afflictions that affect only a small number of people. Therefore it may be time for a more holistic approach; an investigation of systems as a whole, which Systems biology tries to achieve. Science needs to look for commonalities between disease mechanisms wherever possible to enhance the chance of finding common footholds for therapies that target multiple diseases. Unraveling further molecular inter.. View More»
  DOI: 10.4172/2157-7013.1000e109

  Abstract PDF

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