Journal of Medical & Surgical Pathology
Open Access

Arguelles M

Publications

• Research Article
  Androgen Receptor as Prognostic Marker in Triple-Negative Breast Cancer Patients
  Author(s): Cabezas-Quintario MA, Zenzola V, Arguelles M and Pérez-Fernández E Cabezas-Quintario MA, Zenzola V, Arguelles M and Pérez-Fernández E
  
  Purpose: The purpose of this study was to assess the prognostic impact of androgen receptor (AR) expression in patients with triple-negative breast cancer (TNBC). Methods/patients: 101 patients treated for primary TNBC without distant metastasis from 1999 to 2015 were identified from breast surgery database. Kaplan-Meier and Cox regression models evaluated disease-free survival (DFS) and overall survival (OS). Results: AR expression was positive (IHC>1%) in 40% of patients. OS at 36 and 60 months was 86% and 80% in AR-negative patients, and 100% and 96% in AR-positive patients (log rank test 0.036). DFS at 36 and 60 months was 78% and 68% in AR-negative and 92% and 89% in AR-positive (log rank test 0.075). Conclusions: Patients without AR expression have a sign.. View More»
  DOI: 10.4172/2472-4971.1000170

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