Pancreatic Disorders & Therapy
Open Access

Arlen P

Publications

• Review Article
  The Clinical Detection of Pancreatic Carcinoma: A Comparison of the Standard Biomarkers to that of a Newer Class of Biomarkers used for both Diagnosis and Therapy
  Author(s): Arlen M, Arlen P, Wang X, Saric O, Martin DA, Deutsch G and Sathyanaryana SA Arlen M, Arlen P, Wang X, Saric O, Martin DA, Deutsch G and Sathyanaryana SA
  
  One of the characteristics that defines many malignancies that metastasize via the circulatory system, is their ability to shed surface membrane proteins into the blood stream where they can be detected as tumor markers. The primary clinical application associated with defining these tumor markers, many representing carbohydrate antigens, has been in their use for specifically monitoring the status of the patient, in terms of their response to therapy. In the more than 40 years of the clinical measuring what we term tumor markers, none have been defined that are of value in their ability to help the clinician to diagnose the presence of an existing malignancy. Rather, their role has been assigned to that of a monitoring function. It appears essential that the ideal tumor marker, when defined, should be able detect the presence of an established tumor, as well as characterize the clini.. View More»
  DOI: 10.4172/2165-7092.S4-001

  Abstract PDF

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