ISSN: 2167-7700
Armando Sabbatini
Italy
Research Article
Prognostic Factors in Early Stage Non-Small Cell Lung Cancer: The
Importance of Number of Resected Lymph Nodes and Vascular Invasion
Author(s): Rossana Berardi, Alfredo Santinelli, Alessandro Brunelli, Francesca Morgese, Azzurra Onofri, Agnese Savini, Miriam Caramanti, Cecilia Pompili, Michele Salati, Lina Zuccatosta, Paola Mazzanti, Armando Sabbatini, Stefano Gasparini, Italo Bearzi and Stefano CascinuRossana Berardi, Alfredo Santinelli, Alessandro Brunelli, Francesca Morgese, Azzurra Onofri, Agnese Savini, Miriam Caramanti, Cecilia Pompili, Michele Salati, Lina Zuccatosta, Paola Mazzanti, Armando Sabbatini, Stefano Gasparini, Italo Bearzi and Stefano Cascinu
Background: Despite an appropriate surgical treatment, half of early-stage non-small cell lung cancer patients will die due to lung cancer. The number of resected lymph-nodes and vascular invasion has proved to be a prognostic factor in other solid tumors, as well as breast and colorectal cancer. Here we evaluate their prognostic impact in the largest mono-centric series of resected non-small cell lung cancer patients.
Methods: Clinical and pathological characteristics and prognostic outcomes of four hundred thirty-nine consecutive patients undergoingradical surgical resection for non-small cell lung cancer at our Institution were evaluated.
Results: The multivariate analysis showed that number of resected lymph nodes, vascular invasion and sex had a prognostic impact on overall survival. The optimal cut-off number.. View More»
DOI:
10.4172/2167-7700.1000120