Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
+44 1478 350008
ISSN: 2161-1017
+44 1478 350008
Atif E Abd-Elbaky
Egypt
Research Article
Associations of Serum Omentin and Apelin Concentrations with Obesity, Diabetes Mellitus Type 2 and Cardiovascular Diseases in Egyptian Population
Author(s): Atif E Abd-Elbaky, Dina M Abo-ElMatty, Noha M Mesbah and Sherine M IbrahimAtif E Abd-Elbaky, Dina M Abo-ElMatty, Noha M Mesbah and Sherine M Ibrahim
Background and aim: Dysregulation of omentin, a beneficial adipokine and apelin, an inflammatory adipokine, is thought to play a role in the development of type 2 diabetes mellitus and cardiovascular disease. The objective of this study was to evaluate the relationship between circulating omentin and apelin concentrations and components of the metabolic syndrome in adults with and without type 2 diabetes mellitus or cardiovascular disease.
Methods: A total of 240 adults sex and age-matched were included in the current case-control study, including 80 healthy non-obese controls, 80 obese patients with T2DM without cardiovascular disease, and 80 obese patients with T2DM with cardiovascular disease . Fasting blood sample was collected to determine biochemical indicators and insulin resistance index (HOMA-IR). Omentin, apelin, interleukin-1&beta.. View More»
DOI:
10.4172/2161-1017.1000171