Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Atteia Gad Anwar
Egypt
Research Article
Comparative Study between Intravenous Ketamine and Lidocaine Infusion in
Controlling of Refractory Trigeminal Neuralgia
Author(s): Mona Mohamed Mogahed, Atteia Gad Anwar and Rabab Mohamed Mohamed
Mona Mohamed Mogahed, Atteia Gad Anwar and Rabab Mohamed Mohamed
Background: Trigeminal neuralgia (TN) is considered one of the most debilitating disorders. Several medications such as anticonvulsants are available to provide relief from pain. In this study we used either ketamine which acts as an antagonist to N-methyl-d-aspartate receptors, or lidocaine which can block sodium channels in controlling of refractory trigeminal neuralgia.
Aim: The primary outcome of the study was the pain score (The NRS) for pain assessment during the 12-week study period. The secondary outcomes were (1) Amount of analgesic medications (2) Frequency of pain (3) descriptors of pain.
Methods: This study was conducted on 100 adult patients (aged 20-70 years) with refractory trigeminal neuralgia. Patients were enrolled into two groups each group contain 50 patients. In group I (ketamine group), patien.. View More»
DOI:
10.4172/2155-6148.1000746