Journal of Clinical & Experimental Dermatology Research
Open Access

Ayako Shimizu

Publications

• Case Report
  Generalized Pustular Psoriasis Associated with Ulcerative Colitis
  Author(s): Ayako Shimizu, Noriaki Kamada and Hiroyuki Matsue Ayako Shimizu, Noriaki Kamada and Hiroyuki Matsue
  
  A 38-year-old Japanese woman with steroid-dependent ulcerative colitis developed generalized pustular psoriasis. Cyclosporine improved both her cutaneous lesions and bowel condition. Recent studies show that Th17 T cells are critically involved in the pathogenesis of both generalized pustular psoriasis and inflammatory bowel disease. Although molecular mechanisms seem similar, our case is the first report showing generalized pustular psoriasis associated with inflammatory bowel disease. We believe that our case may contribute to further understanding of both diseases and give us a chance to design a suitable therapy in the case of generalized pustular psoriasis complicating inflammatory bowel disease. .. View More»
  DOI: 10.4172/2155-9554.1000192

  Abstract PDF

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