Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Ayse Cikim Sertkaya
Division of Endocrinology and Metabolism, 44315, Inonu University School of Medicine,
Malatya
Turkey
Research Article
The Effect of Hyperthyroidism on Bone Mineral Density in Premenopausal Women
Author(s): Zeynep Zengin and Ayse Cikim Sertkaya
Zeynep Zengin and Ayse Cikim Sertkaya
Background: The effects of subclinical hyperthyroidism and clinical hyperthyroidism on bone metabolism in premenopausal women are contradictory.
Methods: Sixteen hyperthyroid (31.3±9.5 yrs), 23 subclinical hyperthyroid (33.7±7.3 yrs) and 20 healthy (31.7±8.1 yrs) premenopausal women were evaluated. Bone mineral density (BMD) was assessed by dual energy X-ray absorptiometry (DXA). Osteocalcin, total alkaline phosphatase (tALP), homocysteine, β-2 microglobulin, hsCRP and deoxypyridinoline (DPD) concentrations were assessed. Demographic and anthropometrical parameters; and osteoporotic risk factors were evaluated.
Results: Serum calcium, tALP, osteocalcin, β-2 microglobulin and DPD were significantly different in hyperthyroid group. However there was no difference for any of the study pa.. View More»
DOI:
10.4172/2167-7948.1000104