Advanced Techniques in Biology & Medicine
Open Access

C Padmalatha

Publications

• Research Article
  Cytomorphological Changes and Inhibition of Inclusion Body Formation in Leptospira interrogans on Treatment with the Extracts of Adhatoda vasica
  Author(s): Jeyakumar Nelson, K Chairman, AJA Ranjit Singh, Jeyakumar Nelson, K Chairman, AJA Ranjit Singh,
  
  Leptospirosis is most common bacterial zoonosis worldwide, caused by spirochetes of the genus Leptospira that are transmitted from animals to humans. To treat leptospirosis, traditional healers use phytoremedy. In the present study, a scientific study was made on the plants used by the traditional healers to cure liver problems with symptoms of leptospirosis. Methanolic and ethanolic extracts of four plants were screened for antiLeptospiral activity. Of the four plants, Adhatoda vasica extracts exhibited a good anti-Leptospiral activity. On treatment of Leptospira interrogans culture with leaf extracts of the plant Adhatoda vasica, the cellular architechure of lengthy spirochaete L. interrogans was severely damaged. An electron microscopic observation showed breaks at different locations in the lengthy cell, and inhibition of the deve.. View More»
  DOI: 10.4172/2379-1764.1000101

  Abstract PDF

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