Journal of Depression and Anxiety
Open Access

Camila Danielle Aragão-Almeida

Publications

• Research Article
  Are Women Sensitive to the Acute Anxiolytic Effect of Diazepam?
  Author(s): Camila Danielle Aragão-Almeida, Fabrício Dias Antunes, Vânia dos Santos Barbosa, Flavia Teixeira-Silva Camila Danielle Aragão-Almeida, Fabrício Dias Antunes, Vânia dos Santos Barbosa, Flavia Teixeira-Silva
  
  Objective: Several studies have shown the influence of ovarian hormones on the GABAergic system. As women are naturally exposed to monthly fluctuation of these hormones, it is possible that their response to benzodiazepines also change over the ovarian cycle. Bearing this in mind, this study aimed to evaluate the possible influence of the ovarian cycle of healthy women on the acute effect of diazepam. Methods: Forty subjectively healthy women were selected and randomly allocated to two different groups, according to their ovarian cycle phase, follicular (6 to 10 days from the first day of the cycle) or luteal (5 to 10 days after detection of urinary LH peak). Both groups completed the Video-Monitored Stroop Color-Word Test (VMSCWT), an experimental model of anxiety, under the influence of diazepam (10 mg) or placebo. Psychological parameters.. View More»
  DOI: 10.4172/2167-1044.1000235

  Abstract PDF

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