ISSN: 2155-9554
+44 1478 350008
Camille Ozil
France
Research Article
Skin Elasticity in Neurofibromatosis Type 1: Rheological and Histological Analysis
Author(s): Nabila Assoul, Camille Ozil, Romain Bosc, Mickael Hivelin, Mustapha Zidi and Laurent LantieriNabila Assoul, Camille Ozil, Romain Bosc, Mickael Hivelin, Mustapha Zidi and Laurent Lantieri
Neurofibromatosis type 1 (NF1) also known as von Recklinghausen’s disease, is an autosomal dominant disorder characterized by benign tumors called neurofibromas. It is a serious disease, often overlooked. Indeed, people with NF1 have a lower life expectancy, because some of them develop malignant tumors and for many, there is deterioration in their life quality.
In the absence of medical treatment, only surgery is in place for now. However, the problem of neurofibromatosis surgery is that it is potentially very hemorrhagic and neurofibroma skin elasticity seems recurrent after few years.
The aim of this study was to evaluate structure alterations in NF1 skin. At First, mechanical tests that were performed on pathological and control samples have led to the identification of ela.. View More»
DOI:
10.4172/2155-9554.1000213