Anesthesia & Clinical Research
Open Access

Carl-Johan Jakobsen

Publications

• Research Article
  Remifentanil and Sufentanil Preserve Left Ventricular Systolic and Diastolic Function in Patients with Ischemic Heart Disease-A Randomised Comparative Study
  Author(s): Christian A Frederiksen, Peter Juhl-Olsen, Michael Kremke, Linda A Rasmussen, Anne-Grethe Lorenzen, Erik Sloth and Carl-Johan Jakobsen Christian A Frederiksen, Peter Juhl-Olsen, Michael Kremke, Linda A Rasmussen, Anne-Grethe Lorenzen, Erik Sloth and Carl-Johan Jakobsen
  
  Although the impact of drugs on cardiac function seems unchanged by standard haemodynamic measurements, it might be followed by injurious stress and deterioration of myocardial function as stable conventional monitoring not necessarily represent unaffected function. The aim of the study was to assess changes in global haemodynamic measures, primarily by changes in cardiac index, and contemporary indices of LV systolic and diastolic function during induction of anaesthesia with remifentanil compared to sufentanil. The aim was to compare the effect of sufentanil and remifentanil with primary focus on the opioids given as a single drug and secondary in conjunction with Propofol. Methods: Thirty patients with ischaemic heart disease scheduled for elective cardiac surgery were randomized to receive either remifentanil or sufentanil as basic opioid. Cardiac function was evaluated with invas.. View More»
  DOI: 10.4172/2155-6148.1000437

  Abstract PDF

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