ISSN: 2167-0420
Research Article
Prevalence of the Triple-Negative Phenotype in Mexican Patients with Breast Cancer Treated in Private Practice
Author(s): Ana Olivia Cortes-Flores, Gilberto Morgan-Villela, Jorge Jiménez-Tornero, Carlos Zuloaga-Fernández del Valle, Guillermo Juárez- López, Clotilde Fuentes-Orozco, Michel Dassaejv Macías-Amezcua, Rodrigo Ville-Benavides, Ernesto Alejandro Juárez-Uzeta and Alejandro González-Ojeda
Ana Olivia Cortes-Flores, Gilberto Morgan-Villela, Jorge Jiménez-Tornero, Carlos Zuloaga-Fernández del Valle, Guillermo Juárez- López, Clotilde Fuentes-Orozco, Michel Dassaejv Macías-Amezcua, Rodrigo Ville-Benavides, Ernesto Alejandro Juárez-Uzeta and Alejandro González-Ojeda
Background: Identifying the biological profile of breast cancer is fundamental to predict the response to various treatments and for prognosis. The aim of this study was to determine the triple-negative breast cancer prevalence in patients treated in private practice in Mexico.
Methods: The study was performed using Mexican patients older than 18 years and had a histopathological diagnosis of breast adenocarcinoma and immunohistochemical studies for estrogen, progesterone, and HER2/Neu receptors, according to validated standards.
Results: A total of 1,989 patients with a mean age of 52.9 ± 13.4 (23–93) years and a tumor size of 2.72 ± 1.12 cm were evaluated. The TNBC biological subtype was observed in 17.3%, HER2/Neu overexpression in 22.6%, and the presence of positive hormonal receptors (estrogen an.. View More»
DOI:
10.4172/2167-0420.1000170