Biochemistry & Pharmacology: Open Access
Open Access

Changhong Zhang

Publications

• Research Article
  Morbidity of Diabetes Mellitus in Cynomolgus Monkeys
  Author(s): Saimei Yan, Ting Wang, Changhong Zhang, Peng Wang, Xiangting Xu, Jihong Yang and Cui Yang Saimei Yan, Ting Wang, Changhong Zhang, Peng Wang, Xiangting Xu, Jihong Yang and Cui Yang
  
  Object: To determine the morbidity of diabetes mellitus in cynomolgus monkey by performing the Oral Glucose Tolerance Test (OGTT). Method: OGTTs were performed in 600 male cynomolgus monkeys, aging 4-18 years. The values of plasma glucose (PG) and insulin (Ins) were detected. Result: Significant differences were found in the values of PG and Ins among groups with different ages. The values of PG of 4 pathological courses of DM were: Normal glucose tolerance (NGT) group: Fasting plasma glucose (FPG) < 6.10 mmol/L and 2hPG < 7.8 mmol/L; Impaired fasting glucose (IFG) group: 6.10 mmol/L ≤ FPG < 7.0 mmol/L and 2hPG < 7.8 mmol/L; Impaired glucose tolerance (IGT) group: FPG < 7.0 mmol/L and 7.8 mmol/L ≤ 2hPG < 11.1 mmol/L; diabetes mellitus (DM) group: FPG ≥ 7.0 mmol/L or 2hPG ≥ 11.1 mmol/L. The morbidity of diabetes mellitus in the tested cynomol.. View More»
  DOI: 10.4172/2167-0501.1000163

  Abstract PDF

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