Journal of Clinical Toxicology
Open Access

Chinwe S Alisi

Publications

• Research Article
  Renal and Hepato-Protective Effects of Irvingia gabonensis Juice on Sodium Fluoride-Induced Toxicity in Wistar Rats
  Author(s): Adamma A Emejulu, Chinwe S Alisi, Emeka S Asiwe, Chidi U Igwe, Linus A Nwogu and Viola A Onwuliri Adamma A Emejulu, Chinwe S Alisi, Emeka S Asiwe, Chidi U Igwe, Linus A Nwogu and Viola A Onwuliri
  
  Objective: Renal and hepato-protective effects of Irvingia gabonensis juice on sodium fluoride-induced toxicity was assessed in twenty-four male Wistar albino rats. Methodology: The rats were divided into 4 groups of 6 animals each. All except normal control (NC), were intoxicated with 20 mg.Kg-1 body weight of sodium fluoride (NaF) daily by gavage for 35 days. Sodium fluoride control group (NaFC) received only the toxicant. Test group (IG) received I. gabonensis juice concurrently with the toxicant, while the standard control (Q+Vit. E) received concurrently, 15 mg.Kg-1 body weight of Quercetin+100 mg.Kg-1 body weight of α-tocopherol throughout the 35 days. Normal control (NC) group received only standard pelletized diet and water. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, albumin, total cholesterol, serum creatinine and electrolyte .. View More»
  DOI: 10.4172/2161-0495.1000296

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