Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
Chithdavone Her
MINT, UNIV Angers, Université Bretagne Loire,
4 rue Larrey 49933 Angers Cedex 9
France
Review Article
Improvement of Curcumin Bioavailability for Medical Applications
Author(s): Chithdavone Her, Marie-Claire Venier-Julienne and Emilie RogerChithdavone Her, Marie-Claire Venier-Julienne and Emilie Roger
Curcumin, a natural polyphenol isolated from the rhizomes of the turmeric plant (Curcuma longa Linn), is well known for its antioxidant and anti-inflammatory properties. Curcumin is currently marketed as a dietary supplement in several countries (United States, India, Japan, Korea, Thailand, China, Turkey, South Africa, Nepal, and Pakistan). Nevertheless, the use of curcumin has been limited due to its poor aqueous solubility, chemical instability, photodegradation, rapid metabolism, and short half-life. Moreover, orally administered curcumin shows poor bioavailability. Many strategies have been designed to overcome this limitation. In this review, we discuss the bioavailability of curcumin and the commercially available formulations.
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DOI:
10.4172/2167-0412.1000326