Journal of Cell Science & Therapy
Open Access

Christina M. Annunziata

Biography

Dr. Annunziata established mechanisms underlying NF-kappaB molecular signal transduction in ovarian cancer. Her genomic profiling and functional screens identified both downstream targets and upstream regulators of this pathway, defining subgroups of patients whose cancers depend on NF-kappaB, and opening up possibilities for novel therapies to treat ovarian cancer. Her clinical trials emphasize collection of patient samples to better understand both predictive and pharmacodynamic markers of treatment response.

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