Emergency Medicine: Open Access
Open Access
ISSN: 2165-7548
ISSN: 2165-7548
Chung-Ching Chio
People's Republic of China
Research Article
Surgical Site Infection Following Spine Surgery: Diagnostic Potential of CRP,
ESR, and WBC in Predicting Infection
Author(s): Chih-Wei Chen, Varun Puvanesarajah, Sheng-fu L Lo, En-Hsuan Wu, Wen-Tsan Chang, Chung-Ching Chio and Tain-Junn Cheng
Chih-Wei Chen, Varun Puvanesarajah, Sheng-fu L Lo, En-Hsuan Wu, Wen-Tsan Chang, Chung-Ching Chio and Tain-Junn Cheng
Early surgical site infection (SSI) detection could save costs and prevent morbidity. Our aim is to evaluate whether C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), leukocyte count (WBC), or high sensitivity CRP (hsCRP) measurements could effectively predict a SSI, and establish a low-cost method for early diagnosis. This prospective study was conducted at Chi-Mei Medical Center from January 2004 to December 2005. Eligible spinal surgery patients received CRP, ESR, WBC, and hsCRP measurements at pre-specified days. SSI was identified using definitions from the Centers for Disease Control and Prevention and the National Nosocomial Infection Surveillance. Eighty-five patients were enrolled. Four patients experienced SSIs (4.71%). CRP and hsCRP levels from day 2 to 14 demonstrated statistically significantly higher in SSI patients (P<0.001). A threshold CRP value of 25.. View More»
DOI:
10.4172/2165-7548.1000277