Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Chun-Jen Chen
People's Republic of China
Case Report
Childhood Bullous Pemphigoid: A Case Report and Literature Review
Author(s): Chia-Sui Chou, Chien-Lun Hsu, Ming-Luen Lee, Chun-Jen Chen and Ding-Dar Lee and Keh-Gong WuChia-Sui Chou, Chien-Lun Hsu, Ming-Luen Lee, Chun-Jen Chen and Ding-Dar Lee and Keh-Gong Wu
Bullous pemphigoid is a very rare dermatologic disorder in children. We report a 1-year and 9-month-old boy, who was diagnosed childhood bullous pemphigoid on the basis of clinical findings and confirmed by skin biopsy showing subepidermal blisters with dermal layer infiltrated with neutrophils, a unique histological finding. The result mimicked the histological findings of linear immunoglobulin A bullous disease. Direct immunofluorescence showed linear deposits of IgG and C3 at dermal-epidermal junction, similar to epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. We suggested the differential diagnosis of subepidermal blisters should include linear immunoglobulin A bullous disease of childhood, epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. .. View More»
DOI:
10.4172/2155-9554.S6-010