Journal of Clinical & Experimental Dermatology Research
Open Access

Chun-Shin Chang

Publications

• Research Article
  Novel Combination Topical Timolol and Pulsed Dye Laser Therapy for Early Effective Safe Treatment of Infantile Hemangiomas
  Author(s): Chun-Shin Chang, Gavin Chun-Wui Kang Chun-Shin Chang, Gavin Chun-Wui Kang
  
  Introduction: Infantile Hemangiomas (IH) are the most common benign pediatric tumors and carry potential cosmetic and functional sequelae. Topical timolol and Pulsed Dye Laser (PDL) are effective IH therapies and previous studies have suggested the superiority of combination timolol-PDL therapy for IH over timolol alone. We present our experience using combination timolol and PDL therapy for IH, postulate a synergistic effect, and analyze the impact of age on outcomes. Method: Sixteen consecutive children with superficial IH were treated with topical 0.5% timolol. Fourteen responded poorly to one month of timolol-alone treatment and were started on concurrent monthly 595 nm PDL treatment. Outcome was scored at 3 months using a Visual Analog Scale (VAS): 4 for excellent (76-100% improvement), 3 for good (51-75%), 2 for moderate (26-50%), 1 for p.. View More»
  DOI: 10.4172/2155-9554.1000410

  Abstract PDF

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