Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Ciampolillo A
Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases,
Aldo Moro, 70125 Bari
Italy
Research Article
Hashimoto’s Thyroiditis and Nodular Pathology: A Prospective Study in 227 Subjects
Author(s): Ciampolillo A, Barbaro M, Di Trani A, Patruno P and Giorgino FCiampolillo A, Barbaro M, Di Trani A, Patruno P and Giorgino F
The association between Hashimoto’s Thyroiditis (HT) and Papillary Thyroid Carcinoma (PTC) remains controversial. The aim of this prospective study is to determine if there is a risk to develop a thyroid carcinoma in subjects affected by nodular pathology and HT. Methods: 227 subjects (192 females and 35 males) affected by thyroid nodular pathology were submitted to FNAB (Fine Needle Agobiopsy) to define the cytology of the nodules. TSH, and serum anti-thyroid antibodies were measured. If they had positive serum anti-thyroglobulin (Ab anti-TG) and/or anti-thyroperoxidase (Ab anti-TPO) antibodies and had a TSH <4 uUml were included in the study and they were defined as patient affected by autoimmune thyroiditis (HT) in euthyroidism. No patients assumed substitutive therapy with l-thyroxine. All patients gave their informed consent to the study. The patients were classified in .. View More»
DOI:
10.4172/2167-7948.1000145