Journal of Clinical & Experimental Dermatology Research
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• Research Article
  Gender Matter in Isotretinoin Therapy for Acne Vulgaris? A Retrospective Study
  Author(s): Nevena Skroza, Riccardo Pampena, Ersilia Tolino, Sara Zuber, Giorgio La Viola, Nicoletta Bernardini, Ilaria Proietti, Veronica Balduzzi, Fowzieh Rasras, Concetta Potenza Nevena Skroza, Riccardo Pampena, Ersilia Tolino, Sara Zuber, Giorgio La Viola, Nicoletta Bernardini, Ilaria Proietti, Veronica Balduzzi, Fowzieh Rasras, Concetta Potenza
  
  Introduction: Gender differences have been recently highlighted for several aspects of acne vulgaris such as epidemiology, pathogenesis, clinical course, quality of life and treatment outcome. In particular a shorter but more severe clinical course has been reported in males than in females; nevertheless, usually men have their quality of life less affected. Aim: To determine if the response and the adverse events to 1 cycle of oral isotretinoin therapy can be influenced by gender. Methods: A retrospective study was conducted on consecutive patients affected by acne vulgaris and treated with oral isotretinoin. Global acne grading system (GAGS), acne-related quality of life (AQoL) and isotretinoin-related adverse events were considered as outcome measures and were evaluated before (T0), every month during administra.. View More»
  DOI: 10.4172/2155-9554.10000300

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