Chemotherapy: Open Access
Open Access

David Hurd

Publications

• Research Article
  Infectious Complications Associated with the Use of Antithymocyte Globulin in Reduced Intensity Allogeneic Transplants
  Author(s): Kara Loth, Seema Naik, Leanne Kennedy, Gregory Russell, Denise Levitan, Kenneth Zamkoff and David HurdKara Loth, Seema Naik, Leanne Kennedy, Gregory Russell, Denise Levitan, Kenneth Zamkoff and David Hurd
  
  Purpose/Background: Due to its mechanism, the use of antithymocyte globulin (ATG) in reduced intensity conditioning allogeneic stem cell transplant (RIC allo-SCT) therapy may increase the incidence of infection. This study analyzes the type and incidence of infectious complications in RIC allo-SCT patients conditioned with or without ATG. Methodology: Electronic medical records were utilized to identify all adult patients with hematologic malignancies receiving a RIC allo-SCT between January 2001 and December 2010. Patients with aplastic anemia or deceased within 30 days of transplant were excluded. The primary outcome included the rate of infection from engraftment to one year after transplant. Secondarily, the rates of infection during the engraftment period, incidence of acute and chronic GVHD, overall survival, and disease free status at.. View More»
  DOI: 10.4172/2167-7700.100106

  Abstract PDF

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