Journal of Drug Metabolism & Toxicology
Open Access

David J. Watts

Publications

• Case Report
  Serotonin Syndrome: Opportunity for Missed Diagnosis
  Author(s): Daryl J. Di Rocco, Timothy Costello and David J. WattsDaryl J. Di Rocco, Timothy Costello and David J. Watts
  
  Background: Serotonin syndrome is a clinical entity recognized with increasing frequency due to the prevalence with which pro-serotonergic drugs are prescribed and combined across the different medical fields. The common clinical presentation of serotonin syndrome involves autonomic instability, neuromuscular abnormalities, and mental status changes. Objectives: This case report seeks to describe a case where current recommendations regarding observation and disposition could have led to a missed diagnosis and disastrous results. Case Report: We present a 32-year-old female with depression, on daily selective serotonin reuptake inhibitor (SSRI) therapy, who presents after suicide attempt involving the pro-serotonergic agents fluoxetine (80mg) and tramadol (1600mg) and ultimately develops severe serotonin syndrome requiring ICU transfer after remaining essentially asym.. View More»
  DOI: 10.4172/2157-7609.1000109

  Abstract PDF

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