Anatomy & Physiology: Current Research

Anatomy & Physiology: Current Research
Open Access

ISSN: 2161-0940

+44 1300 500008

David Talbert

David Talbert
Imperial College, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, Queen Charlotte’s Hospital,
London W12 ONN
United Kingdom

Publications
  • Review Article
    Cerebral Venous Malformation as a Cause of Neonatal Intra-Ventricular Haemorrhage and Unexplained Infant Subdural Haemorrhage
    Author(s): David Talbert* David Talbert*

    An Intra-ventricular Haemorrhage (IVH) is a bleeding into the brain?s ventricular system. Most intra-ventricular haemorrhages occur in the first 72 hours after birth. They originate in a layer of tissue (Germinal Matrix), under the lining of the ventricles (Ependymal), while it is in the process of manufacturing neurons and glia. This has normally regressed by term but may still be active in premature infants. Pathological investigations have found accumulations of peri-venous plasma and blood suggesting that excessive cerebral venous pressure has disrupted vessels, initiating the intra-ventricular bleeding observed. This has led to unsuccessful searches for evidence of A-V shunts within the developing cerebrum, or loss of auto regulation in arterioles, producing excessive cerebral venous hypertension. An alternative mechanism , reported here, is of venous rather than arterial origin;.. View More»
    DOI: 10.4172/2161-0940.1000202

    Abstract PDF

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