Gynecology & Obstetrics
Open Access

David W Chan

Publications

• Editorial
  The Potential Molecular Therapeutic Approach in Targeting Ovarian Clear Cell Carcinoma
  Author(s): David W Chan and Hextan YS Ngan David W Chan and Hextan YS Ngan
  
  Ovarian Clear Cell Carcinoma (OCCC) is a distinctive subtype of Epithelial Ovarian Cancer (EOC). Compared with other subtypes of EOC, CCC has relatively poor in prognosis and bad outcome in current clinical management using maximal cytoreduction and platinum plus paclitaxel–based combined chemotherapy. Therefore, the investigation of molecular therapeutic approaches targeting at signaling pathways associated with chemoresistance is needed. This review describes some recent potential signaling pathway targets and also suggests putative small molecule kinase inhibitors as well as natural anti-cancer agents in combating this disease. .. View More»
  DOI: 10.4172/2161-0932.1000e103

  Abstract PDF

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