Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Denise Miyamoto
University of São Paulo Medical School, São Paulo-State of São Paulo,
Brazil
Review Article
Sebaceous Cell Carcinoma: A Persistent Challenge in Clinical and Histopathological Diagnosis
Author(s): Denise Miyamoto, Beatrice Wang, Cristina Miyamoto, Valeria Aoki, Li Anne Lim, Paula Blanco and Miguel N BurnierDenise Miyamoto, Beatrice Wang, Cristina Miyamoto, Valeria Aoki, Li Anne Lim, Paula Blanco and Miguel N Burnier
Sebaceous cell carcinoma continues to defy clinicians and pathologists in terms of early diagnosis. The tumor may be mistaken as benign lesions such as chalazion and blepharitis, and also as malignant neoplasms, mainly basal cell carcinoma and squamous cell carcinoma. Despite advances in immunohistochemical analysis and treatment options during the last decades, morbidity and metastasis rates remain high. Prognosis is strongly related to the length of time between diagnosis and initiation of treatment, which reinforces the importance of early recognition of this condition. This article reviews key features of sebaceous cell carcinoma, from epidemiology to treatment, and new strategies to improve outcome.
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DOI:
10.4172/2155-9554.1000353