Orthopedic & Muscular System: Current Research
Open Access

Denisov Lev Nikolaevich

Publications

• Research Article
  Efficacy and Safety of Amtolmetin Guacyl in the Management of Knee Osteoarthritis and Associated Dyspepsia in Routine Clinic Setting: AGATA Study
  Author(s): Nasonov Evgeniy Lvovich, Denisov Lev Nikolaevich, Tsvetkova Elena Sergeevna, Otteva Elvira Nikolaevna, Dubikov Alekzander Ivanovich, Yakupova Svetlana Petrovna, Ivanova Olga Nikolaevna, Korshunov Nikolay Ivanovich, Vaisberg Alexsandra Rudolfovn, Abishev Rashad Azadovich, Tartinov Anton Vladimirovich, Amit Garg, Suhas Khandarkar, Namita Gupta and Shyam AkkuNasonov Evgeniy Lvovich, Denisov Lev Nikolaevich, Tsvetkova Elena Sergeevna, Otteva Elvira Nikolaevna, Dubikov Alekzander Ivanovich, Yakupova Svetlana Petrovna, Ivanova Olga Nikolaevna, Korshunov Nikolay Ivanovich, Vaisberg Alexsandra Rudolfovn, Abishev Rashad Azadovich, Tartinov Anton Vladimirovich, Amit Garg, Suhas Khandarkar, Namita Gupta and Shyam Akku
  
  Aim: To evaluate the efficacy and safety of amtolmetin guacyl in the management of osteoarthritis (OA) of knee and associated dyspepsia in routine clinic setting. Methods: In an observational study conducted in the OA outpatients between February 2015 and December 2015, patients with knee joint (KJ) pain ≥ 40 mm on visual analogue scale (VAS) and dyspepsia were enrolled. Amtolmetin guacyl 600 mg tablets twice daily was administered for up to 28 days. Patients were evaluated at baseline, Day 14 ± 3, and at Day 28 ± 3 for severity of pain in “target” knee (VAS), Western Ontario and Mc master Universities Arthritis (WOMAC) pain and stiffness, and severity of dyspepsia assessment (SODA). Results: Of the 219 OA patients, approximately 72.5% patients reported decrease in pain in the target KJ by &.. View More»
  DOI: 10.4172/2161-0533.1000233

  Abstract PDF

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