Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
+44 1478 350008
ISSN: 2161-0495
+44 1478 350008
Destefani AC
Federal University of Espirito Santo (UFES), Av. Marechal Campos,
1468-Maruipe, Vitória, ES
Brazil
Review Article
Discovering Capacity in Novel Targets: C. Elegans as a Model Life Form in Toxicological Research
Author(s): Destefani AC, Costa DS, Zanardo TEC and Taufner GH
Destefani AC, Costa DS, Zanardo TEC and Taufner GH
The nematode Caenorhabditis elegans has risen as a critical creature show in different fields including neurobiology, formative science, and hereditary qualities. Qualities of this creature demonstrate that have added to its prosperity incorporate its hereditary manipulability, invariant and completely depicted formative program, all around portrayed genome, simplicity of support, short and productive life cycle, and little body estimate. These same elements have prompted to an expanding utilization of C. elegans in toxicology, both for robotic reviews and highthroughput screening approaches. We depict a portion of the exploration that has been completed in the territories of neurotoxicology, hereditary toxicology, and ecological toxicology, and additionally high-throughput tries different things with C. elegans including all inclusive screening for sub-atomic focuses of harmfulness a.. View More»
DOI:
10.4172/2161-0495.1000339