ISSN: 2155-6148
Dewi Yulianti Bisri
Indonesia
Research Article
Glasgow Coma Scale Improvement after Lidocaine Infusion in Moderate
Traumatic Brain Injury
Author(s): Diana Christine Lalenoh and Dewi Yulianti Bisri
Diana Christine Lalenoh and Dewi Yulianti Bisri
Since the Glasgow Coma Scale was developed 40 years ago it has been accepted throughout the world as a method for assessing impaired consciousness.
Fourty moderate TBI patients were simple randomly divided into 2 groups: group A take normal saline infusion without lidocaine as control group (N=20), and group B take normal saline with lidocaine at rate 1 mg/kg/BW infusion as treated groups (N=20). Serum samples were collected at before induction and 2 hours after giving infusion treatment to measure serum IL-6 and PLA2 level, and lidocaine serum concentration. GCS were measured before induction and after 24 hours surgery. Data were analyzed using analytic statistic with paired t test to measure serum IL-6, PLA2, & lidocaine serum level before induction and after 2 hours. The correlation of serum IL-6, PLA2 and GCS was measure with Separman correlation. A P value less than.. View More»
DOI:
10.4172/2155-6148.1000659