Chemotherapy: Open Access
Open Access

Di Wu

Publications

• Research Article
  Influence of Pathologic Complete Response to Induction Chemotherapy on Long-Term Survival of Patients Advanced Squamous Cell Carcinoma of the Oral Cavity Tongue
  Author(s): Xin-rui Zhang, Di Wu, Zhi-min Liu, Xue-kui Liu, Quan-Li, Hao Li, Zhu-ming Guo and Zong-yuan Zeng Xin-rui Zhang, Di Wu, Zhi-min Liu, Xue-kui Liu, Quan-Li, Hao Li, Zhu-ming Guo and Zong-yuan Zeng
  
  Objective: To discuss long-term efficacy of preoperative induction chemotherapy (IC) plus surgery ± radiotherapy in patients with resectable stage III or IV squamous cell carcinoma of the oral cavity tongue (SCCOT). Methods: From June 1996 to December 2005, 73 patients with advanced SCCOT were treated with IC followed by surgery ± radiotherapy, at the Cancer Center of Sun Yat-sen University. The 5-year overall survival (OS), local control and reasons of treatment failure were analyzed retrospectively. Results: 73 patients aged from 22 to 77 years with untreated, clinical T1?4 N0-2M0 SCCOT underwent IC followed by surgery ± radiotherapy. After IC, 17 patients (23.3%) achieved clinical complete response; 44 patients (60.3%) clinical partial response; 12 patients (16.4%) no response or progression, and overall response rate was 89.0% (65/77). On final surgical pathology, 14 patients (19.2%).. View More»
  DOI: 10.4172/2167-7700.1000133

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