Journal of Oceanography and Marine Research
Open Access

Dieter Rehder

Publications

• Review Article
  Vanadate-Dependent Peroxidases in Macroalgae: Function, Applications, and Environmental Impact
  Author(s): Rehder D Rehder D
  
  Vanadate(V)-dependent haloperoxidases VHPOs in marine macroalgae catalyze the 2e- oxidation, by H2O2, of bromide and iodide (X-) to X+ species such as HOX, X2 and X3-. Several other substrates, including sulfides, are also oxidized. In the active center, H2VO4- is covalently attached to the Nε of a histidine residue, an arrangement that has successfully been modeled with synthetic analogs of the active center. Vanadium acts as a Lewis acid, forming an intermediate peroxido/hydroperoxido complex. The X+ species generated by the VHPOs halogenates organics present in seawater, from which halomethanes CH4-nXn (n is chiefly 2 or 1) evolve. Additionally, the hypohalous acids can protect the algae against biofilm formation. Prospective applications point towards this biocidal (anti-bacterial) potential of the peroxidases. The seaweeds further exploit the haloperoxidase activity in th.. View More»
  DOI: 10.4172/2332-2632.1000121

  Abstract PDF

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