Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
Diwekar UM
Center for Uncertain Systems: Tools for Optimization & Management (CUSTOM), Vishwamitra Research Institute,
Clarendon Hills, IL 60514
Tanzania
Research Article
Modeling and Prediction of Outcome for the Superovulation Stage in In-Vitro Fertilization(IVF)
Author(s): Yenkie KM, Diwekar UM and Bhalerao V
Yenkie KM, Diwekar UM and Bhalerao V
Background: IVF is divided into four stages: superovulation, egg-retrieval, fertilization and embryo transfer. The superovulation stage has specific protocols which include daily injections of hormones, decided by regular monitoring and testing involving cost intensive methods like ultrasound, to enable multiple ovulations per menstrual cycle. However, there is a lack of systematic planning and hormonal dosage prediction for successful superovulation using apriori information.
Methods: This work aims at developing a systematic outcome projection method for superovulation based on initial observations in an IVF cycle. The information about the size range and number of follicles was transformed to moment based information using the mathematical approach from crystallization literature. The follicle growth was modeled as a function of injected hormones and the properties of the fo.. View More»
DOI:
10.4172/jfiv.1000122