Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Douglas G Tincello
United Kingdom
Review Article
Cannabinoids and the Urinary Bladder
Author(s): Evangelia Bakali and Douglas G TincelloEvangelia Bakali and Douglas G Tincello
The presence of the Endocannabinoid System (ECS) in the urinary bladder has led to speculation that endocannabinoid-signalling is involved in the signal transduction pathways regulating bladder relaxation and may be involved in pathophysiological processes of the bladder. On the basis of this evidence, it was postulated that the binding of endocannabinoids to the cannabinoid receptors (CB1 and CB2) may result in relaxation of the urinary bladder during the filling phase. Dysregulation of the ECS in human bladder may be responsible for the aetiopathogenesis of Overactive Bladder Syndrome (OAB) and Detrusor Overactivity (DO)... View More»
DOI:
10.4172/2161-0932.1000163