Orthopedic & Muscular System: Current Research

Orthopedic & Muscular System: Current Research
Open Access

ISSN: 2161-0533

+44-77-2385-9429

Dubikov Alekzander Ivanovich

Publications
  • Research Article
    Efficacy and Safety of Amtolmetin Guacyl in the Management of Knee Osteoarthritis and Associated Dyspepsia in Routine Clinic Setting: AGATA Study
    Author(s): Nasonov Evgeniy Lvovich, Denisov Lev Nikolaevich ,Tsvetkova Elena Sergeevna , Otteva Elvira Nikolaevna, Dubikov Alekzander Ivanovich , Yakupova Svetlana Petrovna, Ivanova Olga Nikolaevna , Korshunov Nikolay Ivanovich , Vaisberg Alexsandra Rudolfovn , Abishev Rashad Azadovich , Tartinov Anton Vladimirovich , Amit Garg, SuhNasonov Evgeniy Lvovich, Denisov Lev Nikolaevich ,Tsvetkova Elena Sergeevna , Otteva Elvira Nikolaevna, Dubikov Alekzander Ivanovich , Yakupova Svetlana Petrovna, Ivanova Olga Nikolaevna , Korshunov Nikolay Ivanovich , Vaisberg Alexsandra Rudolfovn , Abishev Rashad Azadovich , Tartinov Anton Vladimirovich , Amit Garg, Suh

    Aim: To evaluate the efficacy and safety of amtolmetin guacyl in the management of osteoarthritis (OA) of knee and associated dyspepsia in routine clinic setting. Methods: In an observational study conducted in the OA outpatients between February 2015 and December 2015, patients with knee joint (KJ) pain ≥ 40 mm on visual analogue scale (VAS) and dyspepsia were enrolled. Amtolmetin guacyl 600 mg tablets twice daily was administered for up to 28 days. Patients were evaluated at baseline, Day 14 ± 3, and at Day 28 ± 3 for severity of pain in “target” knee (VAS), Western Ontario and Mc master Universities Arthritis (WOMAC) pain and stiffness, and severity of dyspepsia assessment (SODA). Results: Of the 219 OA patients, approximately 72.5% patients reported decrease in pain in the target KJ by &.. View More»
    DOI: 10.4172/2161-0533.1000233

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